Middles and Lasts generally get along with everyone, and a harmonious relationship between a Middle and Last born is very likely.  They're a great match because Middles aim to please and will support the Last Born’s desires to pursue their dreams.

They communicate well because the Middle doesn't feel threatened by the Last, and consistent communication is the Last’s natural mode.  The Last Born, being more adventurous, will bring fun into the relationship. Last Borns do need to guard against making their mate the brunt of their jokes. The Last also needs to share the limelight now and then as the Middle has had enough of being left out of it.